The BrightSpec Advantage
“What is it?” and “How much of it is there?” The BrightSpec FT-MRR platform, based on molecular rotational resonance spectroscopy, directly identifies the different components in a complex chemical mixture (with no chromatography needed), answering these two questions in the same rapid measurement. Low matrix interference and precise fingerprinting provide unparalleled molecular specificity. With direct sampling in vacuum, the approach is a ‘green’ alternative to existing techniques of spectroscopy. In addition, low sample vapor pressures (1-5 mTorr) required to obtain baseline resolved spectra offer a gentle approach to sample handling. BrightSpec FT-MRR spectrometers offer greatly shortened method development times, high sample specificity, identification and quantitation of trace components, and greatly reduced use of consumables.
Fourier-transform Molecular Rotational Resonance is a new commercially available technique to provide sensitive, quantitative measurements for chemical identification and structural analysis. The types of analyses required determines the frequencies used as well as the choice of sampling methods (e.g. nozzle cooled or room temperature measurement). BrightSpec instruments can be delivered in either a broadband or targeted configurations. For fundamental and applied research applications, the broadband instrument configuration provides the greatest flexibility for analysis of chemical samples that will be change frequently. For recurring or continuous analyses of known analytes, the targeted instrument configuration provides a low cost, high resolution analysis with excellent method transfer from R&D to QA/QC environments. FT-MRR provides faster chemical analysis insights.
BrightSpec One – FT-MRR for Analytical R&D
BrightSpec One characterizes the chemical composition of complex mixtures, rapidly delivering quantitative information, without the need for preparatory purification or separation. “Dirty” liquids, headspace samples, solids, and gas mixtures are volatilized and introduced directly into the integrated sample cell. With the attributes of high specificity, high dynamic range, and baseline resolution, FT-MRR identifies sample components with almost absolute specificity before standard calibration, even for trace level components. Available sampling accessories add to the base capability of gas sampling, enabling headspace analysis, thermal evolution of solids, and direct volatilization of liquids. Integration with an optional CTC-PAL3 autosampler ensures unattended operation to maximize sample throughput.
- High selectivity
- ID muliple components in complex matrices
- High dynamic range
- Resolve trace components in complex matrices
- Baseline resolution
- Simple pattern matching for chemical ID
- High specificity
- Low false positive ID rates
- Band intensity directly proportional to abundance
- Rapid data acquisition rates
- Minutes for full spectrum
- Seconds for specific bands
BrightSpec Discovery – FT-MRR for Fundamental Research
BrightSpec Discovery incorporates the same spectroscopic engine as BrightSpec One. The difference is in its form factor, with Discovery employing a modular design for increased experimental flexibility. It operates in identical fashion to the BrightSpec One, but can be combined with and networked to other analytical systems. This thoughtful approach to customization enables fundamental and applied research groups to quickly generate insights on complex processes.
- Shares fundamental attributes of BrightSpec One
- Broad analytical capabilities
- Removable sample chamber
- Easy integration of custom sample cells
- Interchangeable excitation source
- Limited frequency flexibility
- Direct signal access for broadband monitoring and digitization
- Implement complex custom data collection sequences
- Full integration with Edgar data collection and analysis software suite
- Maintains ease of use
BrightSpec Chiral Broadband – FT-MRR for Chiral Characterization
BrightSpec Chiral Broadband is an FT-MRR platform used to differentiate diastereomers in mixtures without preparatory purification or separation. With the addition of the optional 3-Wave Mixing technology, enantiomeric excess may be determined. Operating in the microwave frequency range, and using pulsed jet nozzles to prepare rotationally cooled samples, this alternative to chromatography offers a combination of high-resolution, spectrally specific analyses for chiral characterization.
- Spectra relate directly to structure
- Bond angle
- Bond lengths
- High specificity
- Easily distinguish between conformers
- Can analyze complex mixtures
- No need for pure samples
- Chiral analysis
- With addition of 3-Wave mixing technology
- Enantiomeric excess